CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry
Purpose
This multinational, investigator-initiated registry aims to investigate clinical outcomes of patients undergoing transcatheter mitral valve replacement (TMVR). The registry primarily focuses on patients treated with TMVR in real-world clinical practice. Patients evaluated for TMVR but not undergoing the procedure are no longer systematically included. Historical data may include such patients who subsequently underwent alternative treatments, including transcatheter edge-to-edge repair, mitral valve surgery, or medical/conservative therapy.
Conditions
- Mitral Regurgitation
- Mitral Valve Disease
- Mitral Annular Calcification
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- clinically significant mitral insufficiency - patient underwent screening for TMVI - echocardiography data at baseline (and after TMVI, E2E and surgery) - follow-up of at least 30 days
Exclusion Criteria
- age under 18 years
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| Transcatheter Mitral Valve Replacement (TMVR) | Patients with successful TMVR screening, who underwent Transcatheter Mitral Valve Replacement subsequently. All devices may be included. | |
| Mitral transcatheter edge-to-edge repair (M-TEER) | Patients with TMVR screening failure, who subsequently underwent interventional mitral valve edge-to-edge repair. Update: These patients are currently no longer systematically included. | |
| Mitral valve surgery (Surgery) | Patients with TMVR screening failure, who subsequently underwent mitral valve surgery (i.e., mitral valve repair or replacement). Update: These patients are currently no longer systematically included. | |
| Medical/conservative therapy | Patients with TMVR screening failure, who subsequently underwent conservative or optimal medical therapy. Update: These patients are currently no longer systematically included. |
Recruiting Locations
Brigham and Women's Hospital
Boston, Massachusetts 02115
Boston, Massachusetts 02115
Contact:
Tsuyoshi Kaneko, MD
Tsuyoshi Kaneko, MD
More Details
- Status
- Recruiting
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf