Can Food Timing Reduce Your Diabetes Risk?

Purpose

The goal of this clinical trial is to test whether food timing impacts metabolic health in healthy participants. Participants will: - complete 2 inpatient stays - be provided with test meals - have frequent blood draws

Condition

  • Dietary Habits

Eligibility

Eligible Ages
Between 18 Years and 45 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Healthy with no acute or chronic medical and psychiatric disorders - BMI: 18.5-29.9 kg/m2

Exclusion Criteria

  • Smokers, current tobacco or e-cigarette use - Drug or alcohol dependency - Pregnant

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover Assignment
Primary Purpose
Basic Science
Masking
Single (Participant)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Day shift protocol with diet A 		Day shift protocol with diet A condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Day shift protocol - Diet order A-B
    Research participants will be assigned to day shift condition and Diet A-B order condition.
  • Behavioral: Day shift protocol - Diet order B-A
    Research participants will be assigned to day shift condition and Diet B-A order condition.
Experimental
Day shift protocol with diet B 		Day shift protocol with diet B condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Day shift protocol - Diet order A-B
    Research participants will be assigned to day shift condition and Diet A-B order condition.
  • Behavioral: Day shift protocol - Diet order B-A
    Research participants will be assigned to day shift condition and Diet B-A order condition.
Experimental
Night shift protocol with diet A 		Night shift protocol with diet A condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Night shift protocol - Diet order A-B
    Research participants will be assigned to simulated night shift condition and Diet A-B order condition.
  • Behavioral: Night shift protocol - Diet order B-A
    Research participants will be assigned to simulated night shift condition and Diet B-A order condition.
Experimental
Night shift protocol with diet B 		Night shift protocol with diet B condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Night shift protocol - Diet order A-B
    Research participants will be assigned to simulated night shift condition and Diet A-B order condition.
  • Behavioral: Night shift protocol - Diet order B-A
    Research participants will be assigned to simulated night shift condition and Diet B-A order condition.

Recruiting Locations

Brigham and Women's Hospital
Boston, Massachusetts 02115
Contact:
Frank Scheer, PhD
617-732-14
fscheer@bwh.harvard.edu

More Details

Status
Recruiting
Sponsor
Brigham and Women's Hospital

Study Contact

Megan Munn
6175258259
mmunn@bwh.harvard.edu

Detailed Description

The investigators aim to investigate the influence of different food timing, without changing 24-h caloric and nutrient intake, on glucose and fat tolerance and energy expenditure in healthy people on a simulated day or night shift.