AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention
Purpose
AI INFORM is a multicenter randomized trial that will test the hypothesis that providing clinicians information on the presence and amount of coronary artery calcifications (CAC), will result in initiation or intensification of preventive therapies. The study will use a cloud-based artificial intelligence (AI) platform (Nanox.AI) that can analyze non contrast chest CT and estimate the amount of CAC.
Condition
- Coronary Artery Disease
Eligibility
- Eligible Ages
- Between 40 Years and 75 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Patients aged between 40-75 with prior chest CT within last 3 years
Exclusion Criteria
- Prior coronary artery disease - Prior cancer - Other life-limiting condition
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Intervention Model Description
- Randomized controlled trial of two arms, involving notification to providers (vs non-notification)
- Primary Purpose
- Prevention
- Masking
- Single (Outcomes Assessor)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Notification of Coronary Artery Calcification |
Notification to providers of the presence of coronary artery calcification automatically detected by AI based device (software) on chest CT. Recommendation of preventive therapy. |
|
|
No Intervention Non-notification of Coronary Artery Calcification |
No notification to providers of the presence of coronary artery calcification on chest CT automatically detected by AI based device (software) on chest CT. No recommendation of preventive therapy. |
|
Recruiting Locations
Brigham and Women's Hospital
Boston, Massachusetts 02445
Boston, Massachusetts 02445
More Details
- Status
- Recruiting
- Sponsor
- Brigham and Women's Hospital