CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry
Purpose
This multinational, investigator-initiated, retrospective study aims to investigate outcomes of patients, who underwent transcatheter mitral valve implantation (TMVI), in comparison to those screened for TMVI but deemed ineligible, who subsequently underwent interventional mitral valve edge-to-edge repair, mitral valve surgery or medical/conservative therapy.
Condition
- Mitral Regurgitation
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- clinically significant mitral insufficiency - patient underwent screening for TMVI - echocardiography data at baseline (and after TMVI, E2E and surgery) - follow-up of at least 30 days
Exclusion Criteria
- age under 18 years
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| Transcatheter Mitral Valve Implantation (TMVI) | Patients with successful TMVI screening, who underwent Transcatheter Mitral Valve Implantation subsequently. All devices may be included. | |
| Interventional mitral valve edge-to-edge repair (E2E) | Patients with TMVI screening failure, who subsequently underwent interventional mitral valve edge-to-edge repair. | |
| Mitral valve surgery (Surgery) | Patients with TMVI screening failure, who subsequently underwent mitral valve surgery (i.e., mitral valve repair or replacement). | |
| Medical therapy (OMT) | Patients with TMVI screening failure, who subsequently underwent conservative or optimal medical therapy (OMT). |
Recruiting Locations
Brigham and Women's Hospital
Boston, Massachusetts 02115
Boston, Massachusetts 02115
Contact:
Tsuyoshi Kaneko, MD
Tsuyoshi Kaneko, MD
More Details
- Status
- Recruiting
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf