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Purpose

The goal of this clinical trial is to test whether food timing impacts metabolic health in healthy participants. Participants will: - complete 2 inpatient stays - be provided with test meals - have frequent blood draws

Condition

Eligibility

Eligible Ages
Between 18 Years and 45 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Healthy with no acute or chronic medical and psychiatric disorders - BMI: 18.5-29.9 kg/m2

Exclusion Criteria

  • Smokers, current tobacco or e-cigarette use - Drug or alcohol dependency - Pregnant

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover Assignment
Primary Purpose
Basic Science
Masking
Single (Participant)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Day shift protocol with diet A 		Day shift protocol with diet A condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Day shift protocol - Diet order A-B
    Research participants will be assigned to day shift condition and Diet A-B order condition.
  • Behavioral: Day shift protocol - Diet order B-A
    Research participants will be assigned to day shift condition and Diet B-A order condition.
Experimental
Day shift protocol with diet B 		Day shift protocol with diet B condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Day shift protocol - Diet order A-B
    Research participants will be assigned to day shift condition and Diet A-B order condition.
  • Behavioral: Day shift protocol - Diet order B-A
    Research participants will be assigned to day shift condition and Diet B-A order condition.
Experimental
Night shift protocol with diet A 		Night shift protocol with diet A condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Night shift protocol - Diet order A-B
    Research participants will be assigned to simulated night shift condition and Diet A-B order condition.
  • Behavioral: Night shift protocol - Diet order B-A
    Research participants will be assigned to simulated night shift condition and Diet B-A order condition.
Experimental
Night shift protocol with diet B 		Night shift protocol with diet B condition. Since this is a single-blind study, the details of the meal conditions cannot be released during the recruitment stage but will be made public once enrollment closes.
  • Behavioral: Night shift protocol - Diet order A-B
    Research participants will be assigned to simulated night shift condition and Diet A-B order condition.
  • Behavioral: Night shift protocol - Diet order B-A
    Research participants will be assigned to simulated night shift condition and Diet B-A order condition.

Recruiting Locations

Brigham and Women's Hospital
Boston, Massachusetts 02115
Contact:
Frank Scheer, PhD
617-732-14
fscheer@bwh.harvard.edu

More Details

Status
Recruiting
Sponsor
Brigham and Women's Hospital

Study Contact

Megan Munn
6175258259
mmunn@bwh.harvard.edu

Detailed Description

The investigators aim to investigate the influence of different food timing, without changing 24-h caloric and nutrient intake, on glucose and fat tolerance and energy expenditure in healthy people on a simulated day or night shift.

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.